GLP-1 weight loss results.
What to realistically expect from GLP-1 medicines: the trial numbers for Mounjaro, Wegovy, the Wegovy pill and Foundayo, minus the hype.
What to realistically expect from GLP-1 medicines: the trial numbers for Mounjaro, Wegovy, the Wegovy pill and Foundayo, minus the hype. Pharmacy Score is free and independent: every pharmacy it lists is GPhC register-verified, every score is the provider’s real Trustpilot rating, and live GLP-1 prices are one click away via the trackers below.
Marketing loves a big number. Here's what the clinical trials actually measured, average body-weight loss at the highest dose, over roughly 72 weeks, alongside diet and activity changes:
- Mounjaro (tirzepatide): around 20 to 22.5% average at the highest doses, the class leader
- Wegovy injection (semaglutide 2.4mg): around 15%; up to roughly 20% at the 7.2mg dose
- Wegovy pill (oral semaglutide): around 13.6 to 14%
- Foundayo (orforglipron): 11.2% at the highest dose in ATTAIN-1
Reading those numbers honestly
They're averages, individual results spread widely in both directions. They assume consistent use over more than a year. And weight typically returns if the medicine stops without other changes in place, which is why Foundayo's licence covering weight maintenance after injections matters.
Higher efficacy usually means a higher price, but the right medicine is the one a prescriber matches to your health, then you find its best price: Monj · iGovy · oGovy · Dayo.
Live prices, per medication.
The official sources, in one place.
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