Guide
Stopping Treatment.
The honest answer about stopping: what the studies show, and how people keep the weight off.
In short
The honest answer about stopping: what the studies show, and how people keep the weight off.
The blunt truth from the trials: when GLP-1 treatment stops, appetite returns and much of the lost weight typically follows within a year or two. These medicines manage a chronic condition; they don't cure it.
What that means in practice
- Don't stop abruptly without a plan. Talk to your prescriber about tapering and what comes next.
- The habits carry the load. People who hold the loss after stopping are generally those who used treatment to rebuild eating and activity patterns, not just suppress appetite.
- Maintenance options exist. Foundayo's UK licence specifically covers weight maintenance after injectable treatment, a planned "step-down" route to ask your prescriber about. See what is Foundayo?
Cost is a legitimate part of this decision, a medicine you take for years should be bought at the best price going. That's what the trackers are for: Monj.co.uk, iGovy.co.uk, oGovy.co.uk, Dayo.co.uk.
The official sources, in one place.
These are the bodies that actually regulate, appraise and advise. If anything you read anywhere (including here) disagrees with them, believe them.
GPhC register
Check any pharmacy's registration before you order, free and instant.
MHRA: buying medicines online
The regulator's official advice on buying medication safely on the internet.
MHRA Yellow Card
Report a side effect from any medicine, it takes five minutes and it matters.
NICE: semaglutide (TA875)
The evidence-based NHS guidance for Wegovy in weight management.
NICE: tirzepatide (TA1026)
The evidence-based NHS guidance for Mounjaro in weight management.
NHS: obesity
NHS overview of treatment options, including when medicines are considered.
NHS: Better Health
Free NHS support for losing weight, with or without medication.
electronic medicines compendium
The official patient information leaflets for every licensed UK medicine.